On 22nd Mar, 2019, NMPA adds five new alternative testing methods and 4 revised testing methods to Safety and Technical Standards for Cosmetics (2015). The five new alternative testings will be allowed to be used in the New cosmetic ingredients registration process.

The 5 new testing methods:

• Determination of Free Formaldehyde in Cosmetics
• Short Time Exposure In Vitro Test Method (STE)
• Skin Sensitization: Local Lymph Node Assay: DA (LLNA:DA)
• Skin Sensitization: Local Lymph Node Assay: BrdU-ELISA (LLNA:BrdU-ELISA)
• In Chemico Skin Sensitisation: Direct Peptide Reactivity Assay (DPRA)

The 4 revised testing methods:

• Determination of Cantharidin and Chlormethine in Cosmetics,
• Determination of 10 α-hydroxy acid in cosmetics,
• Bacterial Reverse Mutation Assay
• Teratogenicity Test.

From 1st Jan 2020, these testing methods will be available to the testing of cosmetics registration/filing and post-market surveillance.

Source: NMPA News